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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Scavenger receptor class B member 1' and Ligand = 'BDBM50159533'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Scavenger receptor class B member 1


(Homo sapiens (Human))		BDBM50159533
PNG
(CHEMBL3786653)
Show SMILES COc1c(NC(=O)C(=O)c2ccc(OCCNC(=O)CN)c3ccccc23)cc(cc1NS(C)(=O)=O)C(C)(C)C
Show InChI InChI=1S/C28H34N4O7S/c1-28(2,3)17-14-21(26(38-4)22(15-17)32-40(5,36)37)31-27(35)25(34)20-10-11-23(19-9-7-6-8-18(19)20)39-13-12-30-24(33)16-29/h6-11,14-15,32H,12-13,16,29H2,1-5H3,(H,30,33)(H,31,35)
KEGG

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 50n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me...

Bioorg Med Chem Lett 26: 1901-4 (2016)


Article DOI: 10.1016/j.bmcl.2016.03.025
BindingDB Entry DOI: 10.7270/Q22R3TJ2
More data for this
Ligand-Target Pair