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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Scavenger receptor class B member 1' and Ligand = 'BDBM50159547'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Scavenger receptor class B member 1


(Homo sapiens (Human))		BDBM50159547
PNG
(CHEMBL3786659)
Show SMILES [O-]C(=O)C(F)(F)F.CC[N+](CC)(CC)CCCS(=O)(=O)Nc1cc(cc(NC(=O)C(=O)c2ccc(OCCN3CCOCC3)c3ccccc23)c1OC)C(C)(C)C
Show InChI InChI=1S/C38H54N4O7S.C2HF3O2/c1-8-42(9-2,10-3)21-13-25-50(45,46)40-33-27-28(38(4,5)6)26-32(36(33)47-7)39-37(44)35(43)31-16-17-34(30-15-12-11-14-29(30)31)49-24-20-41-18-22-48-23-19-41;3-2(4,5)1(6)7/h11-12,14-17,26-27,40H,8-10,13,18-25H2,1-7H3;(H,6,7)
KEGG

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 158n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me...

Bioorg Med Chem Lett 26: 1901-4 (2016)


Article DOI: 10.1016/j.bmcl.2016.03.025
BindingDB Entry DOI: 10.7270/Q22R3TJ2
More data for this
Ligand-Target Pair