Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase A-Raf' and Ligand = 'BDBM192503'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase A-Raf (Homo sapiens (Human))	BDBM192503 (US9187474, 18) Show SMILES CNc1cc2nc(C)c(cc2cn1)-c1cc(NC(=O)NCCC(C)(C)C)ccc1F Show InChI InChI=1S/C23H28FN5O/c1-14-17(10-15-13-27-21(25-5)12-20(15)28-14)18-11-16(6-7-19(18)24)29-22(30)26-9-8-23(2,3)4/h6-7,10-13H,8-9H2,1-5H3,(H,25,27)(H2,26,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Deciphera Pharmaceuticals, LLC; Eli Lilly and Company US Patent					Assay Description Sample preparation: A375 cells from ATCC are lysed by sonication in commercially available lysis buffer, cleared by centrifugation, and the resulting...				US Patent US9187474 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HWK
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