Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM50026210'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50026210 (CHEMBL1276196) Show SMILES [H][C@]12CN(c3cc(F)c(c(F)c3)-c3ccnc4c(c(nn34)-c3ccncc3)-c3cccc4[nH]ncc34)[C@]([H])(CN1C1CCC1)C2 |r,wU:36.42,1.0,(4.86,-17.8,;3.77,-18.9,;3.78,-20.44,;2.44,-21.22,;2.45,-22.75,;1.12,-23.53,;1.13,-25.07,;-.2,-25.85,;2.46,-25.83,;3.8,-25.06,;5.13,-25.82,;3.79,-23.52,;2.47,-27.37,;1.14,-28.14,;1.14,-29.68,;2.47,-30.45,;3.81,-29.68,;5.28,-30.16,;6.19,-28.9,;5.28,-27.65,;3.81,-28.13,;7.73,-28.9,;8.5,-30.24,;10.04,-30.24,;10.81,-28.9,;10.03,-27.56,;8.5,-27.57,;5.76,-31.62,;7.26,-31.94,;7.74,-33.4,;6.71,-34.55,;5.2,-34.23,;3.95,-35.13,;2.71,-34.22,;3.2,-32.76,;4.73,-32.77,;1.11,-20.46,;-.44,-20.45,;1.1,-18.92,;2.43,-18.13,;2.43,-16.59,;3.51,-15.5,;2.42,-14.42,;1.33,-15.51,;2.19,-19.36,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<0.320	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of BRAF				J Med Chem 53: 7874-8 (2010) Article DOI: 10.1021/jm1007566 BindingDB Entry DOI: 10.7270/Q2HM58Q3
					More data for this Ligand-Target Pair