Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM50215781'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50215781 (2-(pyridin-4-ylmethylamino)-N-(2,2,3,3-tetrafluoro...) Show SMILES FC1(F)Oc2ccc(NC(=O)c3ccccc3NCc3ccncc3)cc2OC1(F)F Show InChI InChI=1S/C21H15F4N3O3/c22-20(23)21(24,25)31-18-11-14(5-6-17(18)30-20)28-19(29)15-3-1-2-4-16(15)27-12-13-7-9-26-10-8-13/h1-11,27H,12H2,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of b-Raf				Bioorg Med Chem Lett 17: 4378-81 (2007) Article DOI: 10.1016/j.bmcl.2007.02.075 BindingDB Entry DOI: 10.7270/Q28K78S7
					More data for this Ligand-Target Pair