Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM14609'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM14609 (N-pyrazinylurea Analog 8d | [(2-chloro-4-{[(5-cyan...) Show SMILES COc1cc(NC(=O)COC(C)=O)c(Cl)cc1NC(=O)Nc1cnc(cn1)C#N Show InChI InChI=1S/C17H15ClN6O5/c1-9(25)29-8-16(26)22-12-4-14(28-2)13(3-11(12)18)23-17(27)24-15-7-20-10(5-19)6-21-15/h3-4,6-7H,8H2,1-2H3,(H,22,26)(H2,21,23,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description Chk1 kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 5uM ATP/[gamma-33P] ATP. 33P incor...				Bioorg Med Chem Lett 16: 2293-8 (2006) Article DOI: 10.1016/j.bmcl.2006.01.028 BindingDB Entry DOI: 10.7270/Q26971TD
					More data for this Ligand-Target Pair