Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM50192407'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50192407 (9-hydroxy-4-methyl-5-phenylpyrrolo[3,4-c]carbazole...) Show SMILES Cc1c2C(=O)NC(=O)c2c2c([nH]c3ccc(O)cc23)c1-c1ccccc1 Show InChI InChI=1S/C21H14N2O3/c1-10-15(11-5-3-2-4-6-11)19-17(18-16(10)20(25)23-21(18)26)13-9-12(24)7-8-14(13)22-19/h2-9,22,24H,1H3,(H,23,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition at human Chk1 in presence of 4 uM ATP				J Med Chem 49: 4896-911 (2006) Article DOI: 10.1021/jm0512591 BindingDB Entry DOI: 10.7270/Q23778BD
					More data for this Ligand-Target Pair