Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM50245257'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50245257 (4-(2-chlorophenyl)-9-hydroxy-6-(3-(4-methylpiperaz...) Show SMILES CN1CCN(CCCn2c3ccc(O)cc3c3c4C(=O)NC(=O)c4c(cc23)-c2ccccc2Cl)CC1 Show InChI InChI=1S/C28H27ClN4O3/c1-31-11-13-32(14-12-31)9-4-10-33-22-8-7-17(34)15-20(22)24-23(33)16-19(18-5-2-3-6-21(18)29)25-26(24)28(36)30-27(25)35/h2-3,5-8,15-16,34H,4,9-14H2,1H3,(H,30,35,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determination				Eur J Med Chem 43: 1276-96 (2008) Article DOI: 10.1016/j.ejmech.2007.07.016 BindingDB Entry DOI: 10.7270/Q26M36MC
					More data for this Ligand-Target Pair