Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM50355599'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50355599 (CHEMBL1910753) Show SMILES Cc1cn2c(\C=N\NC3=[NH+]CC[N-]3)c(nc2s1)-c1ccc(Cl)c(c1)[N+]([O-])=O |t:8| Show InChI InChI=1S/C16H13ClN7O2S/c1-9-8-23-13(7-20-22-15-18-4-5-19-15)14(21-16(23)27-9)10-2-3-11(17)12(6-10)24(25)26/h2-3,6-8H,4-5H2,1H3,(H-,18,19,22)/q-1/p+1/b20-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bologna Curated by ChEMBL					Assay Description Inhibition of CHK1 assessed as inhibition of substrate phosphorylation using fluorescent peptide substrate by microplate reader assay				Eur J Med Chem 46: 4311-23 (2011) Article DOI: 10.1016/j.ejmech.2011.07.001 BindingDB Entry DOI: 10.7270/Q2NG4R1D
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