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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM50414204'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))
BDBM50414204
PNG
(CHEMBL541515)
Show SMILES COc1cc2NC(=O)c3ccc(Nc4cc(F)nc(F)c4)cc3Nc2cc1OCCCCO
Show InChI InChI=1S/C23H22F2N4O4/c1-32-19-11-18-17(12-20(19)33-7-3-2-6-30)27-16-8-13(4-5-15(16)23(31)28-18)26-14-9-21(24)29-22(25)10-14/h4-5,8-12,27,30H,2-3,6-7H2,1H3,(H,26,29)(H,28,31)
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PC cid
PC sid
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Article
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2n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Chk1


J Med Chem 52: 3159-65 (2009)


Article DOI: 10.1021/jm801444x
BindingDB Entry DOI: 10.7270/Q2FF3TM8
More data for this
Ligand-Target Pair