Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM50414204'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50414204 (CHEMBL541515) Show SMILES COc1cc2NC(=O)c3ccc(Nc4cc(F)nc(F)c4)cc3Nc2cc1OCCCCO Show InChI InChI=1S/C23H22F2N4O4/c1-32-19-11-18-17(12-20(19)33-7-3-2-6-30)27-16-8-13(4-5-15(16)23(31)28-18)26-14-9-21(24)29-22(25)10-14/h4-5,8-12,27,30H,2-3,6-7H2,1H3,(H,26,29)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Chk1				J Med Chem 52: 3159-65 (2009) Article DOI: 10.1021/jm801444x BindingDB Entry DOI: 10.7270/Q2FF3TM8
					More data for this Ligand-Target Pair