Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM50414248'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50414248 (CHEMBL549661) Show SMILES CC(C)(O)c1ccc2Nc3cc(Nc4ccnc(Nc5ccnc(Cl)c5)c4)ccc3C(=O)Nc2c1 Show InChI InChI=1S/C26H23ClN6O2/c1-26(2,35)15-3-6-20-22(11-15)33-25(34)19-5-4-16(12-21(19)32-20)30-18-8-10-29-24(14-18)31-17-7-9-28-23(27)13-17/h3-14,32,35H,1-2H3,(H,33,34)(H2,28,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Chk1				J Med Chem 52: 3159-65 (2009) Article DOI: 10.1021/jm801444x BindingDB Entry DOI: 10.7270/Q2FF3TM8
					More data for this Ligand-Target Pair