Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PAK 4' and Ligand = 'BDBM50389123'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM50389123 (CHEMBL2064631) Show SMILES CN(C)C[C@@H](OC(=O)N1Cc2c(NC(=O)C(C)(C)C(F)(F)F)[nH]nc2C1(C)C)c1ccccc1 |r| Show InChI InChI=1S/C23H30F3N5O3/c1-21(2,23(24,25)26)19(32)27-18-15-12-31(22(3,4)17(15)28-29-18)20(33)34-16(13-30(5)6)14-10-8-7-9-11-14/h7-11,16H,12-13H2,1-6H3,(H2,27,28,29,32)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assay				J Med Chem 55: 4728-39 (2012) Article DOI: 10.1021/jm300204j BindingDB Entry DOI: 10.7270/Q2BZ673W
					More data for this Ligand-Target Pair