Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK1' and Ligand = 'BDBM25512'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM25512 (1-[3-(dimethylamino)phenyl]-3-methyl-N-[(1S)-1-phe...) Show SMILES C[C@H](Nc1cc2n(nc(C)c2cn1)-c1cccc(c1)N(C)C)c1ccccc1 |r| Show InChI InChI=1S/C23H25N5/c1-16(18-9-6-5-7-10-18)25-23-14-22-21(15-24-23)17(2)26-28(22)20-12-8-11-19(13-20)27(3)4/h5-16H,1-4H3,(H,24,25)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	977	n/a	n/a	n/a	n/a	7.2	30
Sunesis Pharmaceuticals					Assay Description An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...				Bioorg Med Chem Lett 18: 5648-52 (2008) Article DOI: 10.1016/j.bmcl.2008.08.095 BindingDB Entry DOI: 10.7270/Q29C6VRP
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