Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK1' and Ligand = 'BDBM50232592'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50232592 (CHEMBL4088932) Show SMILES CC[C@H]1N(C(C)C)c2nc(Nc3cc(F)c(cc3OC)C(=O)NC3CN(C)C3)ncc2-n2cnc(C#N)c12 |r| Show InChI InChI=1S/C26H30FN9O2/c1-6-20-23-19(9-28)30-13-35(23)21-10-29-26(33-24(21)36(20)14(2)3)32-18-8-17(27)16(7-22(18)38-5)25(37)31-15-11-34(4)12-15/h7-8,10,13-15,20H,6,11-12H2,1-5H3,(H,31,37)(H,29,32,33)/t20-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Takeda California Curated by ChEMBL					Assay Description Inhibition of human FLAG-tagged PLK1 expressed in baculovirus infected sf21 cells using Biotin-AGAGTVPESIHSFIGDGLV as substrate by TR-FRET assay				Bioorg Med Chem Lett 27: 1311-1315 (2017) Article DOI: 10.1016/j.bmcl.2016.10.009 BindingDB Entry DOI: 10.7270/Q2K939RQ
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