Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK1' and Ligand = 'BDBM91675'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM91675 (Peptide-peptoid hybrid, 6q) Show SMILES CC(C)C[C@@H](NC(=O)CN(CCCCCCc1ccccc1)C(C)=O)C(=O)N[C@H](Cc1cnc[nH]1)C(=O)N[C@H](CO)C(=O)N[C@H]([C@@H](C)OP(O)(O)=O)C(N)=O |r| Show InChI InChI=1S/C35H55N8O11P/c1-22(2)16-27(39-30(46)19-43(24(4)45)15-11-6-5-8-12-25-13-9-7-10-14-25)33(48)40-28(17-26-18-37-21-38-26)34(49)41-29(20-44)35(50)42-31(32(36)47)23(3)54-55(51,52)53/h7,9-10,13-14,18,21-23,27-29,31,44H,5-6,8,11-12,15-17,19-20H2,1-4H3,(H2,36,47)(H,37,38)(H,39,46)(H,40,48)(H,41,49)(H,42,50)(H2,51,52,53)/t23-,27-,28-,29-,31-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Frederick National Lab					Assay Description Pkk1 PDB fluorescence polarization competition binding assay using Plk.				Chembiochem 13: 1291-6 (2012) Article DOI: 10.1002/cbic.201200206 BindingDB Entry DOI: 10.7270/Q2WS8RTH
					More data for this Ligand-Target Pair