Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK1' and Ligand = 'BDBM91676'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM91676 (Peptide-peptoid hybrid, 7) Show SMILES CC(C)C[C@@H](NC(=O)CCCCCCCCc1ccccc1)C(=O)N[C@H](Cc1cnc[nH]1)C(=O)N[C@H](CO)C(=O)N[C@H]([C@@H](C)OP(O)(O)=O)C(N)=O |r| Show InChI InChI=1S/C34H54N7O10P/c1-22(2)17-26(38-29(43)16-12-7-5-4-6-9-13-24-14-10-8-11-15-24)32(45)39-27(18-25-19-36-21-37-25)33(46)40-28(20-42)34(47)41-30(31(35)44)23(3)51-52(48,49)50/h8,10-11,14-15,19,21-23,26-28,30,42H,4-7,9,12-13,16-18,20H2,1-3H3,(H2,35,44)(H,36,37)(H,38,43)(H,39,45)(H,40,46)(H,41,47)(H2,48,49,50)/t23-,26-,27-,28-,30-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Frederick National Lab					Assay Description Pkk1 PDB fluorescence polarization competition binding assay using Plk.				Chembiochem 13: 1291-6 (2012) Article DOI: 10.1002/cbic.201200206 BindingDB Entry DOI: 10.7270/Q2WS8RTH
					More data for this Ligand-Target Pair