Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK2' and Ligand = 'BDBM50343571'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human))	BDBM50343571 ((S)-1-methyl-8-(5-(pyrrolidine-2-carboxamido)-2-(t...) Show SMILES Cn1nc(C(N)=O)c2CCc3cnc(Nc4cc(NC(=O)[C@@H]5CCCN5)ccc4OC(F)(F)F)nc3-c12 |r| Show InChI InChI=1S/C23H23F3N8O3/c1-34-19-13(18(33-34)20(27)35)6-4-11-10-29-22(32-17(11)19)31-15-9-12(5-7-16(15)37-23(24,25)26)30-21(36)14-3-2-8-28-14/h5,7,9-10,14,28H,2-4,6,8H2,1H3,(H2,27,35)(H,30,36)(H,29,31,32)/t14-/m0/s1	PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences srl Curated by ChEMBL					Assay Description Inhibition of PLK2 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting				Bioorg Med Chem Lett 21: 2969-74 (2011) Article DOI: 10.1016/j.bmcl.2011.03.054 BindingDB Entry DOI: 10.7270/Q27M088W
					More data for this Ligand-Target Pair