Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK4' and Ligand = 'BDBM50073548'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK4 (Homo sapiens (Human))	BDBM50073548 (CHEMBL3408952) Show SMILES O=C1Nc2ccccc2[C@]11C[C@H]1c1ccc2c(\C=C\c3ccc(CN4CC5CCC(C4)O5)cc3)n[nH]c2c1 |r| Show InChI InChI=1S/C32H30N4O2/c37-31-32(26-3-1-2-4-29(26)33-31)16-27(32)22-10-13-25-28(34-35-30(25)15-22)14-9-20-5-7-21(8-6-20)17-36-18-23-11-12-24(19-36)38-23/h1-10,13-15,23-24,27H,11-12,16-19H2,(H,33,37)(H,34,35)/b14-9+/t23?,24?,27-,32-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PLK4 (unknown origin) by ELISA				J Med Chem 58: 147-69 (2015) Article DOI: 10.1021/jm5005336 BindingDB Entry DOI: 10.7270/Q2M0475V
					More data for this Ligand-Target Pair