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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase RIPK2' and Ligand = 'BDBM50184478'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase RIPK2


(Homo sapiens (Human))
BDBM50184478
PNG
(CHEMBL3823809)
Show SMILES CS(=O)(=O)c1ccc2nccc(Nc3ccc4[nH]nnc4c3)c2c1
Show InChI InChI=1S/C16H13N5O2S/c1-24(22,23)11-3-5-13-12(9-11)14(6-7-17-13)18-10-2-4-15-16(8-10)20-21-19-15/h2-9H,1H3,(H,17,18)(H,19,20,21)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 50n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...


J Med Chem 59: 4867-80 (2016)


BindingDB Entry DOI: 10.7270/Q2G162SQ
More data for this
Ligand-Target Pair