Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Sgk1' and Ligand = 'BDBM268619'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM268619 (US9718825, Example 15) Show SMILES Clc1cccc(c1Cl)S(=O)(=O)Nc1ccc(cc1)-c1nc(N2CCNCC2)c2cn[nH]c2n1 Show InChI InChI=1S/C21H19Cl2N7O2S/c22-16-2-1-3-17(18(16)23)33(31,32)29-14-6-4-13(5-7-14)19-26-20-15(12-25-28-20)21(27-19)30-10-8-24-9-11-30/h1-7,12,24,29H,8-11H2,(H,25,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.20	n/a	n/a	n/a	n/a	7.4	n/a
SANOFI US Patent					Assay Description The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...				US Patent US9718825 (2017) BindingDB Entry DOI: 10.7270/Q2VM4F82
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