Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM104193'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM104193 (US8575145, 70) Show SMILES CC(C)C1(COc2cccc3ccc(nc23)-c2nnc3ccccn23)CCNCC1 Show InChI InChI=1S/C24H27N5O/c1-17(2)24(11-13-25-14-12-24)16-30-20-7-5-6-18-9-10-19(26-22(18)20)23-28-27-21-8-3-4-15-29(21)23/h3-10,15,17,25H,11-14,16H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.75	n/a	n/a	n/a	n/a	7.4	22
Array BioPharma Inc. US Patent					Assay Description The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...				US Patent US8575145 (2013) BindingDB Entry DOI: 10.7270/Q2M90797
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