Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM110753'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM110753 (US8614206, 286) Show SMILES Cn1ncc(NC(=O)c2nc(sc2N)-c2ccccc2F)c1N1CC[C@H](N)CC(F)(F)C1 |r| Show InChI InChI=1S/C20H22F3N7OS/c1-29-19(30-7-6-11(24)8-20(22,23)10-30)14(9-26-29)27-17(31)15-16(25)32-18(28-15)12-4-2-3-5-13(12)21/h2-5,9,11H,6-8,10,24-25H2,1H3,(H,27,31)/t11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.0100	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
F. Hoffmann-La Roche AG US Patent					Assay Description PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...				US Patent US8614206 (2013) BindingDB Entry DOI: 10.7270/Q2W66JFG
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