Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM110820'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM110820 (US8614206, 371 | US8614206, 372) Show SMILES Cn1ncc(NC(=O)c2nc(sc2N)-c2c(F)cccc2F)c1N1CCC(O)CC(F)(F)C1 Show InChI InChI=1S/C20H20F4N6O2S/c1-29-19(30-6-5-10(31)7-20(23,24)9-30)13(8-26-29)27-17(32)15-16(25)33-18(28-15)14-11(21)3-2-4-12(14)22/h2-4,8,10,31H,5-7,9,25H2,1H3,(H,27,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.00600	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
F. Hoffmann-La Roche AG US Patent					Assay Description PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...				US Patent US8614206 (2013) BindingDB Entry DOI: 10.7270/Q2W66JFG
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM110820 (US8614206, 371 | US8614206, 372) Show SMILES Cn1ncc(NC(=O)c2nc(sc2N)-c2c(F)cccc2F)c1N1CCC(O)CC(F)(F)C1 Show InChI InChI=1S/C20H20F4N6O2S/c1-29-19(30-6-5-10(31)7-20(23,24)9-30)13(8-26-29)27-17(32)15-16(25)33-18(28-15)14-11(21)3-2-4-12(14)22/h2-4,8,10,31H,5-7,9,25H2,1H3,(H,27,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.0150	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
F. Hoffmann-La Roche AG US Patent					Assay Description PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...				US Patent US8614206 (2013) BindingDB Entry DOI: 10.7270/Q2W66JFG
					More data for this Ligand-Target Pair