Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM191113'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM191113 (US9181258, 134) Show SMILES CN(C)Cc1ccc(cc1)-c1c(cc2C(=O)NC[C@H](CCCN)n12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C26H29F3N4O2/c1-32(2)16-17-8-10-18(11-9-17)24-22(19-5-3-7-21(13-19)35-26(27,28)29)14-23-25(34)31-15-20(33(23)24)6-4-12-30/h3,5,7-11,13-14,20H,4,6,12,15-16,30H2,1-2H3,(H,31,34)/t20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec...				US Patent US9181258 (2015) BindingDB Entry DOI: 10.7270/Q2862F7F
					More data for this Ligand-Target Pair