Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM191114'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM191114 (US9181258, 135) Show SMILES CN1CCN(Cc2ccc(cc2)-c2c(cc3C(=O)NC[C@H](CCCN)n23)-c2cccc(OC(F)(F)F)c2)CC1 Show InChI InChI=1S/C29H34F3N5O2/c1-35-12-14-36(15-13-35)19-20-7-9-21(10-8-20)27-25(22-4-2-6-24(16-22)39-29(30,31)32)17-26-28(38)34-18-23(37(26)27)5-3-11-33/h2,4,6-10,16-17,23H,3,5,11-15,18-19,33H2,1H3,(H,34,38)/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec...				US Patent US9181258 (2015) BindingDB Entry DOI: 10.7270/Q2862F7F
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