Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM191120'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM191120 (US9181258, 126 | US9181258, 129) Show SMILES COc1ccc(cc1Cl)-c1c(cc2C(=O)NC[C@H](CCN)n12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C23H21ClF3N3O3/c1-32-20-6-5-14(10-18(20)24)21-17(13-3-2-4-16(9-13)33-23(25,26)27)11-19-22(31)29-12-15(7-8-28)30(19)21/h2-6,9-11,15H,7-8,12,28H2,1H3,(H,29,31)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec...				US Patent US9181258 (2015) BindingDB Entry DOI: 10.7270/Q2862F7F
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM191120 (US9181258, 126 | US9181258, 129) Show SMILES COc1ccc(cc1Cl)-c1c(cc2C(=O)NC[C@H](CCN)n12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C23H21ClF3N3O3/c1-32-20-6-5-14(10-18(20)24)21-17(13-3-2-4-16(9-13)33-23(25,26)27)11-19-22(31)29-12-15(7-8-28)30(19)21/h2-6,9-11,15H,7-8,12,28H2,1H3,(H,29,31)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.5	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec...				US Patent US9181258 (2015) BindingDB Entry DOI: 10.7270/Q2862F7F
					More data for this Ligand-Target Pair