Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM191122'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM191122 (US9181258, 128) Show SMILES COc1c(C)cc(cc1C)-c1c(cc2C(=O)NC[C@H](CCN)n12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C25H26F3N3O3/c1-14-9-17(10-15(2)23(14)33-3)22-20(16-5-4-6-19(11-16)34-25(26,27)28)12-21-24(32)30-13-18(7-8-29)31(21)22/h4-6,9-12,18H,7-8,13,29H2,1-3H3,(H,30,32)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.5	n/a
NERVIANO MEDICAL SCIENCES S.R.L. US Patent					Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec...				US Patent US9181258 (2015) BindingDB Entry DOI: 10.7270/Q2862F7F
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