Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM149686'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM149686 (US8975267, 22) Show SMILES CSc1ncc2CCc3c(cn(C(C)C)c3-c2n1)C(N)=O Show InChI InChI=1S/C15H18N4OS/c1-8(2)19-7-11(14(16)20)10-5-4-9-6-17-15(21-3)18-12(9)13(10)19/h6-8H,4-5H2,1-3H3,(H2,16,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	7.5	n/a
Nerviano Medical Sciences S.r.l. US Patent					Assay Description The buffer for PIM-2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 microM Na3VO4, and 0.2 mg/mL BSAFull-length human PIM...				US Patent US8975267 (2015) BindingDB Entry DOI: 10.7270/Q29C6W41
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