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Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM26705'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-2


(Homo sapiens (Human))
BDBM26705
PNG
(7-chloro-9-ethyl-6-fluoro-1-(2-hydroxyethyl)-1H,3H...)
Show SMILES CCn1c2n(CCO)oc(=O)c2c(=O)c2cc(F)c(Cl)cc12
Show InChI InChI=1S/C14H12ClFN2O4/c1-2-17-10-6-8(15)9(16)5-7(10)12(20)11-13(17)18(3-4-19)22-14(11)21/h5-6,19H,2-4H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.42E+3>-33.0n/an/an/an/an/a7.522



Abbott Laboratories



Assay Description
Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...


Bioorg Med Chem Lett 18: 5206-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.079
BindingDB Entry DOI: 10.7270/Q2833QBF
More data for this
Ligand-Target Pair