Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM35015'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM35015 (benzothienopyrimidinone deriv., 13c) Show SMILES CN(C)Cc1nc2c3cc(ccc3sc2c(=O)[nH]1)C#CCCCCN1CCCCC1 Show InChI InChI=1S/C24H30N4OS/c1-27(2)17-21-25-22-19-16-18(11-12-20(19)30-23(22)24(29)26-21)10-6-3-4-7-13-28-14-8-5-9-15-28/h11-12,16H,3-5,7-9,13-15,17H2,1-2H3,(H,25,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	23	-43.6	n/a	n/a	n/a	n/a	n/a	n/a	25
Abbott Laboratories					Assay Description In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...				J Med Chem 52: 6621-36 (2009) Article DOI: 10.1021/jm900943h BindingDB Entry DOI: 10.7270/Q27P8WQW
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