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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM35039'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-2


(Homo sapiens (Human))
BDBM35039
PNG
(benzothienopyrimidinone deriv., 17a)
Show SMILES CN(C)Cc1nc2c3cc(ccc3sc2c(=O)[nH]1)N1CCCC1
Show InChI InChI=1S/C17H20N4OS/c1-20(2)10-14-18-15-12-9-11(21-7-3-4-8-21)5-6-13(12)23-16(15)17(22)19-14/h5-6,9H,3-4,7-8,10H2,1-2H3,(H,18,19,22)
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
5 -47.4n/an/an/an/an/an/a25



Abbott Laboratories



Assay Description
In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...


J Med Chem 52: 6621-36 (2009)


Article DOI: 10.1021/jm900943h
BindingDB Entry DOI: 10.7270/Q27P8WQW
More data for this
Ligand-Target Pair