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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM35046'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-2


(Homo sapiens (Human))
BDBM35046
PNG
(benzothienopyrimidinone deriv., 20a)
Show SMILES O[C@H]1CCN(Cc2nc3c4cc(ccc4sc3c(=O)[nH]2)-c2ccsc2)C1 |r|
Show InChI InChI=1S/C19H17N3O2S2/c23-13-3-5-22(8-13)9-16-20-17-14-7-11(12-4-6-25-10-12)1-2-15(14)26-18(17)19(24)21-16/h1-2,4,6-7,10,13,23H,3,5,8-9H2,(H,20,21,24)/t13-/m0/s1
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
3 -48.6n/an/an/an/an/an/a25



Abbott Laboratories



Assay Description
In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...


J Med Chem 52: 6621-36 (2009)


Article DOI: 10.1021/jm900943h
BindingDB Entry DOI: 10.7270/Q27P8WQW
More data for this
Ligand-Target Pair