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Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM50021623'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase pim-2


(Homo sapiens (Human))		BDBM50021623
PNG
(CHEMBL3297768)
Show SMILES C[C@@H](CN1CCN(C)CC1)NC(=O)C[C@H]1CNC(=O)c2cc(cn12)-c1cccc(Cl)c1 |r|
Show InChI InChI=1S/C23H30ClN5O2/c1-16(14-28-8-6-27(2)7-9-28)26-22(30)12-20-13-25-23(31)21-11-18(15-29(20)21)17-4-3-5-19(24)10-17/h3-5,10-11,15-16,20H,6-9,12-14H2,1-2H3,(H,25,31)(H,26,30)/t16-,20-/m0/s1
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Similars
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Nerviano Medical Sciences

Curated by ChEMBL


Assay Description
Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...

Bioorg Med Chem 21: 7364-80 (2013)


Article DOI: 10.1016/j.bmc.2013.09.054
BindingDB Entry DOI: 10.7270/Q23F4R7S
More data for this
Ligand-Target Pair