Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM161994'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM161994 (US9682991, 43) Show SMILES CN1CCOc2c1c(NCC1CC[C@H](O)CC1)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1 |r,wD:13.14,(-4.57,1.93,;-3.24,2.69,;-3.24,4.23,;-1.91,5,;-.57,4.23,;-.57,2.69,;-1.91,1.93,;-1.91,.38,;-3.24,-.38,;-3.24,-1.93,;-4.57,-2.69,;-4.57,-4.23,;-5.91,-5,;-7.24,-4.23,;-8.57,-5,;-7.24,-2.69,;-5.91,-1.92,;-.57,-.38,;.76,.38,;2.23,-.09,;3.13,1.15,;2.23,2.4,;.76,1.93,;2.62,-1.58,;1.54,-2.67,;1.93,-4.15,;3.42,-4.55,;4.51,-3.46,;6,-3.86,;7.09,-2.77,;8.57,-3.17,;6.69,-1.29,;8.18,-1.69,;4.11,-1.98,)| Show InChI InChI=1S/C22H25F3N6O3/c1-30-9-10-33-18-17(30)19(26-12-13-5-7-15(32)8-6-13)29-31-20(27-28-21(18)31)14-3-2-4-16(11-14)34-22(23,24)25/h2-4,11,13,15,32H,5-10,12H2,1H3,(H,26,29)/t13?,15-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-3 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair