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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM162004'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM162004
PNG
(US9682991, 59)
Show SMILES CN1CCOc2c1c(NCC1CC3(C1)CCNCC3)nn1c(nnc21)-c1cccc(OC(F)(F)F)c1
Show InChI InChI=1S/C24H28F3N7O2/c1-33-9-10-35-19-18(33)20(29-14-15-12-23(13-15)5-7-28-8-6-23)32-34-21(30-31-22(19)34)16-3-2-4-17(11-16)36-24(25,26)27/h2-4,11,15,28H,5-10,12-14H2,1H3,(H,29,32)
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III

US Patent


Assay Description
The biochemical assay to measure PIM-3 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...

US Patent US9682991 (2017)


BindingDB Entry DOI: 10.7270/Q2513WCB
More data for this
Ligand-Target Pair