Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM225040'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM225040 (US9321756, 2) Show SMILES Nc1nnc(o1)-c1ccc2[nH]cc(-c3cncc(n3)N3CCC(F)(F)CC3)c2c1 Show InChI InChI=1S/C19H17F2N7O/c20-19(21)3-5-28(6-4-19)16-10-23-9-15(25-16)13-8-24-14-2-1-11(7-12(13)14)17-26-27-18(22)29-17/h1-2,7-10,24H,3-6H2,(H2,22,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.08	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2
					More data for this Ligand-Target Pair