Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM248938'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM248938 (US9434725, 169 | US9434725, 185 | US9434725, 193) Show SMILES CC1CN(CCN1)c1cccc(n1)-n1ncc2cnc(cc12)-c1cncc(C)n1 Show InChI InChI=1S/C21H22N8/c1-14-9-22-12-18(26-14)17-8-19-16(10-24-17)11-25-29(19)21-5-3-4-20(27-21)28-7-6-23-15(2)13-28/h3-5,8-12,15,23H,6-7,13H2,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0220	-60.8	n/a	n/a	n/a	n/a	n/a	7.2	25
F. HOFFMANN-LA ROCHE AG US Patent					Assay Description PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...				US Patent US9434725 (2016) BindingDB Entry DOI: 10.7270/Q2CF9P1N
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM248938 (US9434725, 169 | US9434725, 185 | US9434725, 193) Show SMILES CC1CN(CCN1)c1cccc(n1)-n1ncc2cnc(cc12)-c1cncc(C)n1 Show InChI InChI=1S/C21H22N8/c1-14-9-22-12-18(26-14)17-8-19-16(10-24-17)11-25-29(19)21-5-3-4-20(27-21)28-7-6-23-15(2)13-28/h3-5,8-12,15,23H,6-7,13H2,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0350	-59.7	n/a	n/a	n/a	n/a	n/a	7.2	25
F. HOFFMANN-LA ROCHE AG US Patent					Assay Description PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...				US Patent US9434725 (2016) BindingDB Entry DOI: 10.7270/Q2CF9P1N
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM248938 (US9434725, 169 | US9434725, 185 | US9434725, 193) Show SMILES CC1CN(CCN1)c1cccc(n1)-n1ncc2cnc(cc12)-c1cncc(C)n1 Show InChI InChI=1S/C21H22N8/c1-14-9-22-12-18(26-14)17-8-19-16(10-24-17)11-25-29(19)21-5-3-4-20(27-21)28-7-6-23-15(2)13-28/h3-5,8-12,15,23H,6-7,13H2,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.164	-55.9	n/a	n/a	n/a	n/a	n/a	7.2	25
F. HOFFMANN-LA ROCHE AG US Patent					Assay Description PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...				US Patent US9434725 (2016) BindingDB Entry DOI: 10.7270/Q2CF9P1N
					More data for this Ligand-Target Pair