Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM248964'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM248964 (US9434725, 195 | US9434725, 203 | US9434725, 204) Show SMILES CC1C(N)CCCN1c1cccc(n1)-n1ncc2cnc(cc12)-c1cncc(C)n1 Show InChI InChI=1S/C22H24N8/c1-14-10-24-13-19(27-14)18-9-20-16(11-25-18)12-26-30(20)22-7-3-6-21(28-22)29-8-4-5-17(23)15(29)2/h3,6-7,9-13,15,17H,4-5,8,23H2,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0250	-60.5	n/a	n/a	n/a	n/a	n/a	7.2	25
F. HOFFMANN-LA ROCHE AG US Patent					Assay Description PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...				US Patent US9434725 (2016) BindingDB Entry DOI: 10.7270/Q2CF9P1N
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM248964 (US9434725, 195 | US9434725, 203 | US9434725, 204) Show SMILES CC1C(N)CCCN1c1cccc(n1)-n1ncc2cnc(cc12)-c1cncc(C)n1 Show InChI InChI=1S/C22H24N8/c1-14-10-24-13-19(27-14)18-9-20-16(11-25-18)12-26-30(20)22-7-3-6-21(28-22)29-8-4-5-17(23)15(29)2/h3,6-7,9-13,15,17H,4-5,8,23H2,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0570	-58.5	n/a	n/a	n/a	n/a	n/a	7.2	25
F. HOFFMANN-LA ROCHE AG US Patent					Assay Description PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...				US Patent US9434725 (2016) BindingDB Entry DOI: 10.7270/Q2CF9P1N
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM248964 (US9434725, 195 | US9434725, 203 | US9434725, 204) Show SMILES CC1C(N)CCCN1c1cccc(n1)-n1ncc2cnc(cc12)-c1cncc(C)n1 Show InChI InChI=1S/C22H24N8/c1-14-10-24-13-19(27-14)18-9-20-16(11-25-18)12-26-30(20)22-7-3-6-21(28-22)29-8-4-5-17(23)15(29)2/h3,6-7,9-13,15,17H,4-5,8,23H2,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.331	-54.1	n/a	n/a	n/a	n/a	n/a	7.2	25
F. HOFFMANN-LA ROCHE AG US Patent					Assay Description PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...				US Patent US9434725 (2016) BindingDB Entry DOI: 10.7270/Q2CF9P1N
					More data for this Ligand-Target Pair