Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM376822'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376822 (N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N(C)c1ccc2nccn2c1 |r| Show InChI InChI=1S/C30H30FN7O/c1-18-11-19(13-20(32)12-18)23-7-8-33-16-27(23)36-30(39)24-4-5-26(31)25-14-22(15-35-29(24)25)37(2)21-3-6-28-34-9-10-38(28)17-21/h3-10,14-20H,11-13,32H2,1-2H3,(H,36,39)/t18-,19+,20-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376822 (N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N(C)c1ccc2nccn2c1 |r| Show InChI InChI=1S/C30H30FN7O/c1-18-11-19(13-20(32)12-18)23-7-8-33-16-27(23)36-30(39)24-4-5-26(31)25-14-22(15-35-29(24)25)37(2)21-3-6-28-34-9-10-38(28)17-21/h3-10,14-20H,11-13,32H2,1-2H3,(H,36,39)/t18-,19+,20-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				Citation and Details BindingDB Entry DOI: 10.7270/Q20V8GZM
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376822 (N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N(C)c1ccc2nccn2c1 |r| Show InChI InChI=1S/C30H30FN7O/c1-18-11-19(13-20(32)12-18)23-7-8-33-16-27(23)36-30(39)24-4-5-26(31)25-14-22(15-35-29(24)25)37(2)21-3-6-28-34-9-10-38(28)17-21/h3-10,14-20H,11-13,32H2,1-2H3,(H,36,39)/t18-,19+,20-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 641-62 (2007) BindingDB Entry DOI: 10.7270/Q2MP55J7
					More data for this Ligand-Target Pair