Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM50131267'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50131267 (CHEMBL3634759 | US9260425, 222) Show SMILES Cn1cc(cn1)-c1cc2c(n[nH]c2cn1)-c1cccc(c1)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C21H23N7/c1-27-12-15(10-24-27)19-9-18-20(11-23-19)25-26-21(18)14-4-2-6-17(8-14)28-7-3-5-16(22)13-28/h2,4,6,8-12,16H,3,5,7,13,22H2,1H3,(H,25,26)/t16-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of Pim3 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins				Bioorg Med Chem Lett 25: 5258-64 (2015) Article DOI: 10.1016/j.bmcl.2015.09.052 BindingDB Entry DOI: 10.7270/Q2TT4SR7
					More data for this Ligand-Target Pair