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Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM50161838'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))
BDBM50161838
PNG
(CHEMBL3792922)
Show SMILES Cc1cc(nc(N)n1)-c1ccncc1NC(=O)c1nc(ccc1N)-c1nccs1
Show InChI InChI=1S/C19H16N8OS/c1-10-8-14(27-19(21)24-10)11-4-5-22-9-15(11)26-17(28)16-12(20)2-3-13(25-16)18-23-6-7-29-18/h2-9H,20H2,1H3,(H,26,28)(H2,21,24,27)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
<3n/an/an/an/an/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Inhibition of Pim3 (unknown origin) using BAD peptide preincubated for 15 mins followed by ATP addition measured after 60 to 100 mins by Kinase-Glo r...


Bioorg Med Chem Lett 26: 2328-32 (2016)


Article DOI: 10.1016/j.bmcl.2016.03.037
BindingDB Entry DOI: 10.7270/Q2WD42F0
More data for this
Ligand-Target Pair