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Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM50266642'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM50266642
PNG
(CHEMBL4097308)
Show SMILES Cc1cncc(n1)-c1ccc2cnn(-c3cccc(n3)N3CCCNCC3)c2c1
Show InChI InChI=1S/C22H23N7/c1-16-13-24-15-19(26-16)17-6-7-18-14-25-29(20(18)12-17)22-5-2-4-21(27-22)28-10-3-8-23-9-11-28/h2,4-7,12-15,23H,3,8-11H2,1H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
 0.200n/an/an/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of PIM3 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins in presence of ATP by caliper microfluidic mobility shift as...

J Med Chem 60: 4458-4473 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00418
BindingDB Entry DOI: 10.7270/Q2H997PN
More data for this
Ligand-Target Pair