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Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-3' and Ligand = 'BDBM50299245'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))
BDBM50299245
PNG
(7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...)
Show SMILES Brc1ccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c2c1
Show InChI InChI=1S/C15H9BrN2O/c16-9-1-4-13-12(5-9)11-3-2-10-8(7-19)6-17-14(10)15(11)18-13/h1-7,17-18H
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Clermont Universit£

Curated by ChEMBL


Assay Description
Inhibition of Pim-3


J Med Chem 52: 6369-81 (2009)


Article DOI: 10.1021/jm901018f
BindingDB Entry DOI: 10.7270/Q23F4PPS
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))
BDBM50299245
PNG
(7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...)
Show SMILES Brc1ccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c2c1
Show InChI InChI=1S/C15H9BrN2O/c16-9-1-4-13-12(5-9)11-3-2-10-8(7-19)6-17-14(10)15(11)18-13/h1-7,17-18H
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

US Patent
n/an/a 40n/an/an/an/an/an/a



Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II

US Patent


Assay Description
Inhibition assay using PIM-1, PIM-2 and PIM-3.


US Patent US8481586 (2013)


BindingDB Entry DOI: 10.7270/Q2ZC81GT
More data for this
Ligand-Target Pair