BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with Target = 'Serine racemase' and Ligand = 'BDBM14673'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Serine racemase (Mus musculus)	BDBM14673 (Fragment 3 \| Malonic Acid \| propanedioic acid) Show SMILES OC(=O)CC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of mouse serine racemase by Lineweaver-Burk plot				Eur J Med Chem 89: 189-97 (2014) Article DOI: 10.1016/j.ejmech.2014.10.043 BindingDB Entry DOI: 10.7270/Q22N53WK
					More data for this Ligand-Target Pair
Serine racemase (Homo sapiens (Human))	BDBM14673 (Fragment 3 \| Malonic Acid \| propanedioic acid) Show SMILES OC(=O)CC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Binding affinity to serine recemase (unknown origin)				Bioorg Med Chem Lett 24: 3732-5 (2014) Article DOI: 10.1016/j.bmcl.2014.07.003 BindingDB Entry DOI: 10.7270/Q2PR7XNR
University of Toyama Curated by ChEMBL					More data for this Ligand-Target Pair
Serine racemase (Homo sapiens (Human))	BDBM14673 (Fragment 3 \| Malonic Acid \| propanedioic acid) Show SMILES OC(=O)CC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Parma Curated by ChEMBL					Assay Description Inhibition of human recombinant serine racemase expressed in Escherichia coli Rosetta 2 (DE3) cells using L-serine as substrate by horseradish peroxi...				Bioorg Med Chem Lett 25: 4297-303 (2015) Article DOI: 10.1016/j.bmcl.2015.07.081 BindingDB Entry DOI: 10.7270/Q2CV4KHX
University of Parma Curated by ChEMBL					More data for this Ligand-Target Pair
Serine racemase (Homo sapiens (Human))	BDBM14673 (Fragment 3 \| Malonic Acid \| propanedioic acid) Show SMILES OC(=O)CC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Parma Curated by ChEMBL					Assay Description Inhibition of hexa-His-tagged purified human recombinant serine racemase expressed in Escherichia coli BL21 Codonplus (DE3)-RIL cells assessed as red...				Bioorg Med Chem Lett 25: 4297-303 (2015) Article DOI: 10.1016/j.bmcl.2015.07.081 BindingDB Entry DOI: 10.7270/Q2CV4KHX
University of Parma Curated by ChEMBL					More data for this Ligand-Target Pair
Serine racemase (Mus musculus)	BDBM14673 (Fragment 3 \| Malonic Acid \| propanedioic acid) Show SMILES OC(=O)CC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	7.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic Chemistry and Biochemistry of the ASCR Curated by ChEMBL					Assay Description Inhibition of mouse recombinant serine racemase transfected in bacterial expression system				J Med Chem 52: 6032-41 (2009) Article DOI: 10.1021/jm900775q BindingDB Entry DOI: 10.7270/Q29G5NRV
					More data for this Ligand-Target Pair
Serine racemase (Homo sapiens (Human))	BDBM14673 (Fragment 3 \| Malonic Acid \| propanedioic acid) Show SMILES OC(=O)CC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kitasato University Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...				J Med Chem 56: 1894-907 (2013) Article DOI: 10.1021/jm3017865 BindingDB Entry DOI: 10.7270/Q2H70H4P
Kitasato University Curated by ChEMBL					More data for this Ligand-Target Pair
Serine racemase (Mus musculus)	BDBM14673 (Fragment 3 \| Malonic Acid \| propanedioic acid) Show SMILES OC(=O)CC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis				Eur J Med Chem 89: 189-97 (2014) Article DOI: 10.1016/j.ejmech.2014.10.043 BindingDB Entry DOI: 10.7270/Q22N53WK
					More data for this Ligand-Target Pair
Serine racemase (Homo sapiens (Human))	BDBM14673 (Fragment 3 \| Malonic Acid \| propanedioic acid) Show SMILES OC(=O)CC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.31E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of full length human recombinant serine recemase C2DC6D mutant expressed in Escherichia coli BL21 (DE3) assessed as D-serine production af...				Bioorg Med Chem Lett 24: 3732-5 (2014) Article DOI: 10.1016/j.bmcl.2014.07.003 BindingDB Entry DOI: 10.7270/Q2PR7XNR
University of Toyama Curated by ChEMBL					More data for this Ligand-Target Pair