BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine-protein kinase ATM' and Ligand = 'BDBM50144952'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine-protein kinase ATM


(Homo sapiens (Human))		BDBM50144952
PNG
(CHEMBL3765095)
Show SMILES COc1cc2ncnc(-n3nc(nc3N)-c3ccccn3)c2cc1OCCCNC(=O)OCC(C)(C)C
Show InChI InChI=1S/C25H30N8O4/c1-25(2,3)14-37-24(34)28-10-7-11-36-20-12-16-18(13-19(20)35-4)29-15-30-22(16)33-23(26)31-21(32-33)17-8-5-6-9-27-17/h5-6,8-9,12-13,15H,7,10-11,14H2,1-4H3,(H,28,34)(H2,26,31,32)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.90E+3n/an/an/an/an/an/a



Duke University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of ATM kinase in human MCF7 cells after 1 hr by immunofluorescence assay

J Med Chem 59: 559-77 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01092
BindingDB Entry DOI: 10.7270/Q2TM7D0W
More data for this
Ligand-Target Pair