Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine-protein kinase ATM' and Ligand = 'BDBM50144987'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine-protein kinase ATM (Homo sapiens (Human))	BDBM50144987 (CHEMBL3764633) Show SMILES COc1cc2nc(N)nc(-n3nc(nc3N)-c3ccccn3)c2cc1OC Show InChI InChI=1S/C17H16N8O2/c1-26-12-7-9-11(8-13(12)27-2)21-16(18)23-15(9)25-17(19)22-14(24-25)10-5-3-4-6-20-10/h3-8H,1-2H3,(H2,18,21,23)(H2,19,22,24)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Duke University School of Medicine Curated by ChEMBL					Assay Description Inhibition of ATM kinase in human MCF7 cells after 1 hr by immunofluorescence assay				J Med Chem 59: 559-77 (2016) Article DOI: 10.1021/acs.jmedchem.5b01092 BindingDB Entry DOI: 10.7270/Q2TM7D0W
					More data for this Ligand-Target Pair