new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serotonin receptor (2b and 2c)' and Ligand = 'BDBM50257612'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin receptor (2b and 2c)


(Homo sapiens (Human))
BDBM50257612
PNG
(CHEMBL493950 | N-benzyl-N-methyl-2,3,4,5-tetrahydr...)
Show SMILES CN(Cc1ccccc1)S(=O)(=O)c1ccc2CCNCCc2c1
Show InChI InChI=1S/C18H22N2O2S/c1-20(14-15-5-3-2-4-6-15)23(21,22)18-8-7-16-9-11-19-12-10-17(16)13-18/h2-8,13,19H,9-12,14H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>9.94E+3n/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant 5HT2B receptor by cell-based system


Bioorg Med Chem Lett 19: 1871-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.071
BindingDB Entry DOI: 10.7270/Q2GB23XH
More data for this
Ligand-Target Pair