Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serum paraoxonase/arylesterase 1' and Ligand = 'BDBM82185'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human))	BDBM82185 (Sulfosalazine, 3) Show SMILES OC(=O)c1ccc(cc1O)\N=N\c1ccc(cc1)S(=O)(=O)Nc1ccccn1 Show InChI InChI=1S/C18H14N4O5S/c23-16-11-13(6-9-15(16)18(24)25)21-20-12-4-7-14(8-5-12)28(26,27)22-17-3-1-2-10-19-17/h1-11,23H,(H,19,22)(H,24,25)/b21-20+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5.70E+5	n/a	2.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Atatürk University					Assay Description The inhibitory effects of six sulfonamide derivatives was examined against the purified enzyme hPON1 and were tested in a triplicate experiment in fi...				Chem Biol Drug Des 76: 552-8 (2010) Article DOI: 10.1111/j.1747-0285.2010.01036.x BindingDB Entry DOI: 10.7270/Q2Q52N3T
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