Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50007400 (4-Phenyl-1-(4-phenyl-butyl)-piperidine | 4-Phenyl-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description The compound was tested for its binding affinity towards Sigma opioid receptor in guinea pig brain membranes | J Med Chem 34: 3360-5 (1992) BindingDB Entry DOI: 10.7270/Q2MC8XZR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50007400 (4-Phenyl-1-(4-phenyl-butyl)-piperidine | 4-Phenyl-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Curated by ChEMBL | Assay Description Binding affinity against sigma receptor in bovine cerebellum using 2.0 nM [3H]-haloperidol in the presence of 25 nM unlabeled spiperone | J Med Chem 36: 3923-8 (1994) BindingDB Entry DOI: 10.7270/Q2H13122 | |||||||||||
More data for this Ligand-Target Pair |