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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sigma non-opioid intracellular receptor 1' and Ligand = 'BDBM50016291'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))		BDBM50016291
PNG
(CHEMBL3262788)
Show SMILES COc1cc2CCN(CCCCNC(=O)c3cc(ccc3OCC#C)C#N)Cc2cc1OC
Show InChI InChI=1S/C26H29N3O4/c1-4-13-33-23-8-7-19(17-27)14-22(23)26(30)28-10-5-6-11-29-12-9-20-15-24(31-2)25(32-3)16-21(20)18-29/h1,7-8,14-16H,5-6,9-13,18H2,2-3H3,(H,28,30)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 3.68E+3n/an/an/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Displacement of (+)-[3H]pentazocine from sigma-1 receptor in guinea pig brain membrane homogenate after 90 mins by liquid scintillation counting anal...

J Med Chem 57: 4239-51 (2014)


Article DOI: 10.1021/jm5001453
BindingDB Entry DOI: 10.7270/Q20P11KX
More data for this
Ligand-Target Pair